地址：中国浙江宁波市江北区风华路818号 邮编：315211 电话：+86-574-87600674
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技术支持：宁波甬讯通信息科技有限公司
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个人简介
主要从事药物化学和有机化学的研究。近期研究重点主要包括天然产物及其衍生物的合成，含氮杂环化合物及其金属络合物的合成，含氟及荧光探针分子的合成。
学习和工作经历
2009.09-2013.06 河南科技学院 制药工程学士
2013.09-2018.08 韩国岭南大学 药物化学博士
2018.10-2020.10 清华大学 化学博士后
2020.12- 至今 宁波大学 新药技术研究院 助理研究员
近年发表的主要论文
1. Ruxin Li#, Juan Zheng#, Yule Wang, Wenjun Bai, Yang Lu*, Jiahou Geng, Jiahe Feng, Ning Wang*, Yufen Zhao, Jinhui Wang*. A novel nitroreductase-responsive turn-off fluorescent probe based on AIEgen and its bioimaging application. Journal of Molecular Structure. 2023, 1294, 136483.
2. Zhiying Hou, Yang Lu*, Bin Zhang, A.F.M. Motiur Rahman, Yufen Zhao, Ning Xi, Ning Wang*, Jinhui Wang*. Investigation of the relationship between electronic structures and bioactivities of polypyridyl Ru(II) complexes. Molecules. 2023, 28, 5035.
3. Wenjun Bai, Yixuan Li, Li Zhao, Ruxin Li, Jiahou Geng, Yang Lu*, Yufen Zhao, Jinhui Wang*. Rational design of a ratiometric fluorescent probe for imaging lysosomal nitroreductase activity. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2023, 302, 123032.
4. Yang Lu, Mingming Sun, Ning Xi*. 19F NMR Chemical Shifts Are Sensitive to Remote Functional Group Variations. Journal of Molecular Structure. 2023, 1283,135273.
5. Yang Lu*, Zhiying Hou, Mengshan Li, Ning Wang, Jinhui Wang, Feng Ni, Yufen Zhao, Bin Zhang*, Ning Xi*. Increasing the cytotoxicity of Ru(ii) polypyridyl complexes by tuning the electron-donating ability of 1,10-phenanthroline ligands. Dalton Transactions. 2022, 51, 16224-16235.
6. Yang Lu, Mingming Sun, Ning Xi*. Effects of fluorine bonding and nonbonding interactions on F-19 chemical shifts. RSC Advances. 2022, 12, 32082-32096.
7. Yang Lu*, Bin Zhang*, Ning Wang, Mengshan Li, Ning Xi*. Investigation of Major Flavonoids from Artemisia argyi as a Potential COVID-19 Drug: Molecular Docking and DFT Calculations. Crystals. 2022, 12, 990.
8.Yang Lu, Dongdong Zhang*, Jinbei Wei, Ziyang Liu, Chen Zhang, Yuewei Zhang, Xiao Li, Hyuna Lee, Jang Hyuk Kwon, Xuewen Wang, Lian Duan*. Bee-shaped Host with Ideal Polarity and Energy Levels for High-efficiency Blue and White Fluorescent OLEDs. Chemical Engineering Journal. 2021, 411, 128457.
9.Yang Lu, Ziyang Liu, Yuewei Zhang, Chen Zhang, Jinbei Wei, Zhengyang Bin, Xuewen Wang, Dongdong Zhang*, Lian Duan*. Suppressing competitive coordination reaction for ohmic cathode contact using amino-substituted organic ligands and air-stable metals. CCS Chemistry. 2021, 3, 367–376.
10.Yang Lu, Wencui Yin, Mohammad Sayed Alam, Adnan A. Kadi, Yurngdong Jahng, Youngjoo Kwon*, A. F. M. Motiur Rahman*. Cyclic Diarylheptanoids: Synthesis, Biological Evaluation and SARs Studies as Potential Anticancer Therapeutics. Anti-Cancer Agents in Medicinal Chemistry. 2020, 20 (4), 464-475.
11.Yang Lu, Yurngdong Jahng*. Preparation of a New Friedländer Synthon, 2,3-Diaminobenzene-1,4-dicarbaldehyde, and Its Application towards Synthesis of 1,10-Phenanthrolines and Related Cyclophane. Chinese Journal of Chemistry. 2019, 37(3), 221-225.
12.Yang Lu, Yurngdong Jahng*. Dinitration of p-Xylene and Practical Separation of 2,3-, 2,5-, and 2,6-Dinitro-p-xylenes. Yakhak Hoeji. 2018, 62(5), 362-365. (KCI）
13.Yang Lu, Karim Moinul, Yurngdong Jahng*. Synthesis and Properties of 2,2’-oxybis(1,10-phenanthroline) and 2,4-dioxa-1,3(2,9)-diphenanthrolin- acyclobutaphane. Bulletin of the Korean Chemical Society. 2018, 39(8), 1015-1018.
14.A. F. M. Motiur Rahman*#, Yang Lu#, Hwa-Jong Lee, Hyunji Jo, Wencui Yin, Mohammad Sayed Alam, Adnan A. Kadi, Youngjoo Kwon, Yurngdong Jahng*. Linear Diarylhepatonoids: Synthesis, Biological Evaluation and SARs Studies as Potential Anticancer Therapeutics. Archives of Pharmacal Research. 2018, 41(12), 1131-1148.
15.Yang Lu, A. F. M. Motiur Rahman, Yurngdong Jahng*, Studies on the reactions of 3,2'-polymethylene-2-phenylbenzo[b]-1,10-phenanthrolines with Ru(tpy)Cl3 and properties of the products. Archives of Pharmacal Research. 2017, 40 (5), 563-570.
近年主持/参与的项目
1. 宁波大学-范恩柯尔联合实验室 - 主持
2. 硼化合物用于硼中子俘获疗法的研发 - 主持
已获授权的发明专利
The method of synthesis 1,10-phenanthroline and its derivatives（10-2018-0106335） - Yurngdong Jahng, Yang Lu
一种新型有机化合物及其应用(201911001008.9) - 段炼，卢洋，张东东
著作编写
略
学术兼职
Biosensors, Frontiers in Chemistry, Current Organic Chemistry 等SCI期刊审稿人
