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个人简介
郭静,2012年获得四川大学应用化学专业学士学位,2018年获得四川大学有机化学专业博士学位,方向为不对称合成。2018-2020年在多伦多大学从事博士后研究,方向为主族化学催化和无机化学。2020年11月入职宁波大学新药技术研究院,任副研究员。期间在Angew. Chem. Int. Ed., Chem. Sci., Org. Lett., Chem. Commun., Chem.-Eur. J., Adv. Synth. Catal.和Org. Biomol. Chem.等高水平期刊发表23篇论文。2020年11月入职宁波大学新药技术研究院,任副研究员。
学习和工作经历
2008.09-2012.06 四川大学,应用化学学士
2012.09-2018.06 四川大学,有机化学博士
2018.11-2020.11 多伦多大学,无机化学博士后
2020.11-至今 宁波大学新药技术研究院,副研究员
近年发表的主要论文
1.W. H. Song,† J. Guo,*,† and D. W. Stephan*. “B(C6F5)3-catalyzed Wolff rearrangement/[2+2] and [4+2] cascade cyclization of α-diazoketones with imines”, Org. Chem. Front., 2023, 10, 1754–1758.
2.L. Xiao,† L. N. Jin,† Y. B. Zhao, J. Guo,* and D. W. Stephan*. “B(C6F5)3-catalyzed cyclopropanation of 3-alkenyl-oxindoles with diazomethanes”, Chem. Commun., 2023, 59, 1833–1836.
3.L. N. Jin, X. Zhou, Y. B. Zhao, J. Guo,* and D. W. Stephan*. “Highly tunable regioselective N-H versus O-H or C-H insertion of 2-hydroxybenzothiazoles with diazoalkanes”, Org. Biomol. Chem. 2022, 20, 7781–7786.
4.Y. B. Zhao, L. N. Jin, J. Guo,* and D. W. Stephan*. “Catalytic hydroaminations of alkynes: a facile protocol to vinyl-carbazole derivatives via a frustrated Lewis pair mechanism”, Chem. Commun., 2022, 58, 3039–3042.
6.Y. B. Zhao, D. Mandal, J. Guo,* Y. Wu and D. W. Stephan*. “B(C6F5)3-Catalyzed site-selective N1-alkylationof benzotriazoles with diazoalkanes”, Chem. Commun., 2021, 57, 7758–7761.
7.W. L. Xiao, Y. H. Mo, J. Guo, Z. S. Su, S. X. Dong*, X. M. Feng*. “Catalytic enantioselective synthesis of macrodiolides and their application in chiral recognition”, Chem. Sci. 2021, 2940–2947.
8.J. Guo, O. Cheong, K. L. Bamford, J. L. Zhou and D. W. Stephan*. “Frustrated Lewis pair-catalyzed double hydroarylation of alkynes with N-substituted pyrroles”, Chem. Commun. 2020, 56, 1855–1858.
9.J. Guo, K. L. Bamford, D. W. Stephan*. “9-Borabicyclo[3.3.l]nonane-induced Friedel–Crafts benzylation of arenes with benzyl fluorides”, Org. Biomol. Chem. 2019, 17, 5258–5261.
10.J. Guo, X. H. Liu*, C. Q. He, F. Tan, S. X. Dong, X. M. Feng*. “Nickel(II)-catalyzed enantioselective α-alkylation of β-ketoamides with phenyliodonium ylide via a radical process”, Chem. Commun. 2018, 54, 12254–12257.
11.J. Guo, Y. B. Liu, X. Q. Li, X. H. Liu*, L. L. Lin, X. M. Feng*. “Nickel(II)-Catalyzed Enantioselective Cyclopropanation of 3-Alkenyl-Oxindoles with Phenyliodonium Ylide via Free Carbene”, Chem. Sci. 2016, 7, 2717–2721.
12.J. Guo, L. L. Lin, Y. B. Liu, X. Q. Li, X. H. Liu*, X. M. Feng*. “Nickel(II)-Catalyzed Enantioselective α-Vinylation of β-Keto Amides/Esters with Hypervalent Iodine Salts”, Org. Lett. 2016, 18, 5540–5543.
13.J. Guo, S. X. Dong, Y. L. Zhang, Y. L. Kuang, X. H. Liu, L. L. Lin, X. M. Feng*. “Chiral Scandium(III)-Catalyzed Enantioselective α-Arylation of N-Unprotected 3-Substituted Oxindoles with Diaryliodonium Salts”, Angew. Chem. Int. Ed. 2013, 52, 10245–10249. Highlighted by Chin. J. Org. Chem. 2013, 33, 2441.
14.J. Guo, X. H. Liu, L. L. Lin, X. M. Feng*. “Recent Development of Catalytic Asymmetric Reaction Using Hypervalent Iodine Reagents”, China science & technology magazine online (2014) P1–12.
15.X. Q. Li, J. Guo, L. L. Lin*, H. P. Hu, F. Z. Chang, X. H. Liu, X. M. Feng*. “Chiral Magnesium(II) Complex-Catalyzed Enantioselective Desymmetrization of meso-Aziridines with Pyrazoles”, Adv. Synth. Catal. 2017, 359, 3532–3539.
16.Y. B. Liu, X. H. Liu*, H. P. Hu, J. Guo, Y. Xia, L. L. Lin, X. M. Feng*. “Synergistic Kinetic Resolution and Asymmetric Propargyl Claisen Rearrangement for the Synthesis of Chiral Allenes”, Angew. Chem. Int. Ed. 2016, 55, 4054–4058.
17.H. P. Hu, Y. B. Liu, J. Guo, L. L. Lin, Y. L. Xu, X. H. Liu, X. M. Feng*. “Enantioselective Synthesis of Dihydrocoumarin Derivatives by Chiral Scandium(III)-Complex Catalyzed Inverse-Electron-Demand Hetero-Diels–Alder Reaction”, Chem. Commun. 2015, 51, 3835–3837.
18.W. D. Cao, X. H. Liu, J. Guo, L. L. Lin, X. M. Feng*. “Asymmetric Tandem 1,5-Hydride Shift/Ring Closure for the Synthesis of Chiral Spirooxindole Tetrahydroquinolines”, Chem. Eur. J. 2015, 21, 1632–1636.
19.X. H. Zhao, X. H. Liu*, H. J. Mei, J. Guo, L. L. Lin, X. M. Feng*. “Asymmetric Dearomatization of Indoles through a Michael/Friedel–Crafts-Type Cascade to Construct Polycyclic Spiroindolines”, Angew. Chem. Int. Ed. 2015, 54, 4032–4035.
20.Y. L. Zhang, N. Yang, X. H. Liu, J. Guo, X. Y. Zhang, L. L. Lin, C. W. Hu, X. M. Feng*. “Reversal of Enantioselective Friedel–Crafts C3-Alkylation of Pyrrole by Slightly Tuning the Amide Units of N,N′-Dioxide Ligands”, Chem. Commun. 2015, 51, 8432–8435.
21.R. X. Peng, L. L. Lin*, W. D. Cao, J. Guo, X. H. Liu, X. M. Feng*. “A Racemic N,N′-Dioxide-iron(III) Complex Chemosensor for Determination of Enantiomeric Excess, Concentration and Identity of Hydroxy Carboxylic Acids with Circular Dichroism and Fluorescence Responses”, Tetrahedron Lett. 2015, 56, 3882–3885.
22.J. L. Zhang, Y. L. Zhang, X. H. Liu, J. Guo, W. D. Cao, L. L. Lin, X. M. Feng*. “Enantioselective Protonation by Aza-Michael Reaction between Pyrazoles and a-Substituted Vinyl Ketones”, Adv. Synth. Catal. 2014, 356, 3545–3550.
23.M. Y. Yan,† L. Xiao,† J. K. Xiong, L. N. Jin, D. W. Stephan* and J. Guo*. “Borane catalyzed transesterification of tert-butyl esters using α-aryl α-diazoesters”, Org. Biomol. Chem., 2023, 21, 8279–8283.
24.J. K. Xiong,† M. Y. Yan,† L. N. Jin, W. H. Song, L. Xiao, D. Xu, C. Y. Zhai, * D. W. Stephan* and J. Guo*. “B(C6F5)3-catalyzed hydrogermylation of enones: a facile route to germacycles”, Org. Biomol. Chem., 2023, 21, 8098–8101.
近年主持/参与的项目
宁波市自然科学基金青年项目(2023/06-2026/05) - 主持
已获授权的发明专利
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著作编写
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学术兼职
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